Polymorphism of interleukin 28b gene as the monitoring parameter of the epidemiological surveillance system for Hepatitis C
نویسندگان
چکیده
منابع مشابه
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Polymorphism Near the Interleukin-28B Gene and Anti-Hepatitis C Viral Response
In a recent genome-wide association study, single nucleotide polymorphisms (SNPs) located near the interleukin-28B gene (IL28B), which encodes type III interferon (IFN) λ3, were shown to be strongly associated with a viral response to pegylated IFNα (PEG-IFNα) and ribavirin (RBV) combination therapy and spontaneous viral clearance in patients chronically and acutely infected with hepatitis C vi...
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15 صفحه اولAssociation of Hepatitis C Virus Infection and Interleukin-28B Gene Polymorphism in Chinese Children
OBJECTIVE To preliminarily explore the association of rs12979860 and rs8099917 SNPs with chronic HCV infection in Chinese Han children. METHODS Chronic HCV infection patients (n=277; 1-17 years old, 4.5 years old in average) and healthy subjects (n=150, children; 2-17 years old, 5.2 years old in average) were recruited and tested by PCR combining direct sequencing. The differences between the...
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ژورنال
عنوان ژورنال: Epidemiology and Infectious Diseases
سال: 2015
ISSN: 2411-3026,1560-9529
DOI: 10.17816/eid40841